Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies
Summary: Recognition of N-linked glycan at residue N276 (glycan276) at the periphery of the CD4-binding site (CD4bs) on the HIV-envelope trimer is a formidable challenge for many CD4bs-directed antibodies.To understand how Personal Hygiene this glycan can be recognized, here we isolate two lineages of glycan276-dependent CD4bs antibodies.Antibody C